The use of jet mills to process APIs is the mainstream of the market
Raw material drug powder generally refers to products with a product particle size of less than 20μm. Airflow pulverization of micropowder is an operation process of pulverizing larger particles or powders into smaller particles or powders. Generally, the product size after pulverization is required to be less than 20μm. Its purpose is to reduce the particle size, increase the specific surface area, and increase the distribution range of the required particle size.
Jet mills are mainly divided into two types: collision type and cyclone type. Its working principle is to use compressed air (or nitrogen) as power, the material is accelerated in the pulverizer for high-speed movement, and the material particles collide with the inner chamber of the pulverizer to achieve pulverization. The main purpose is to change the particle size and Its surface activity and so on. The particle size of the material can be crushed to between 1μm and 100μm.
The characteristics of the API jet mill are:
1. This equipment is made of stainless steel 316 and stainless steel 304.
2. The inside of the equipment is finely polished 0.25-0.5 microns to meet the polishing requirements of different parts.
3. All equipment adopts quick pipe clamp interface connection, which is easy to disassemble and install, and easy to clean.
4. The equipment adopts movable casters, which is easy to move.
5. Except for the feeder, this equipment does not require electricity for other parts, and can be produced only by providing compressed air.
6. The equipment processing capacity is 0.5-30kg/h.
7. The finest pulverization fineness d100<3 microns.
8. It can solve the problems of sticking and blocking of viscous materials and strong static materials.
9. The equipment is airtight, there is almost no loss of raw materials, and the collection rate is high; the equipment has good airtightness, no leakage, and little damage to operators.
10. The equipment has low operating noise. Under normal production conditions, the equipment noise is very low, less than 63dB.
11. The raw materials produced can be directly connected to the packaging bag according to the requirements, which can avoid the leakage caused by the transfer process of the raw materials from the tank to the packaging bag, and avoid the damage to the human body and the leakage loss of the sticky wall of the material.
12. Compared with other equipment, the jet mill has lower energy consumption and smaller nozzle aperture.
13. It can provide a crushing cavity with a very narrow particle size distribution.
14. According to requirements, different Laval nozzles can be provided with different spray angles.
15. The crushing pressure can be up to 1.6Mpa.
16. There is no back-blowing phenomenon, our crushing disc pressure and feeding pressure, no matter which pressure is high, there will be no back-blowing phenomenon.