{"id":113728,"date":"2021-11-12T14:35:27","date_gmt":"2021-11-12T06:35:27","guid":{"rendered":"https:\/\/www.alpapowder.com\/113728\/"},"modified":"2021-11-12T15:20:19","modified_gmt":"2021-11-12T07:20:19","slug":"cin-tibbi-ultra-ince-ogutme-teknolojisi","status":"publish","type":"post","link":"https:\/\/www.alpapowder.com\/tr\/113728\/","title":{"rendered":"\u00c7in t\u0131bb\u0131 ultra ince \u00f6\u011f\u00fctme teknolojisi"},"content":{"rendered":"

Geleneksel \u00c7in t\u0131bb\u0131n\u0131n ultra ince \u00f6\u011f\u00fct\u00fclmesi ile ilgili olarak, ara\u015ft\u0131rmac\u0131lar, ultra ince \u00c7in t\u0131bb\u0131 par\u00e7ac\u0131klar\u0131, tek aromal\u0131 \u00c7in t\u0131bb\u0131 ultra ince par\u00e7alar\u0131 ve ultra ince \u00c7in t\u0131bb\u0131 tozlar\u0131 gibi farkl\u0131 ara\u015ft\u0131rma perspektiflerinden farkl\u0131 isimler ve kavramlar vermi\u015flerdir. Bitki t\u0131bb\u0131n\u0131n ve hayvan t\u0131bb\u0131n\u0131n etkili bile\u015fenleri esas olarak h\u00fccrede ve h\u00fccreler aras\u0131 maddede ve esas olarak h\u00fccrede da\u011f\u0131t\u0131ld\u0131\u011f\u0131ndan, baz\u0131 insanlar \u00c7in t\u0131bbi malzemelerinin h\u00fccrelerini par\u00e7alamak amac\u0131yla “h\u00fccre d\u00fczeyinde mikro” olarak adland\u0131r\u0131l\u0131r. \u00c7in t\u0131bb\u0131n\u0131n toz haline getirilmesi”. Mikro \u00f6\u011f\u00fctme y\u00f6ntemiyle elde edilen geleneksel \u00c7in t\u0131bb\u0131 tozuna “h\u00fccre dereceli \u00c7in t\u0131bb\u0131 tozu” denir. Benzer \u015fekilde, h\u00fccre d\u00fczeyinde \u00c7in t\u0131bb\u0131 tozu temelinde haz\u0131rlanan geleneksel \u00c7in t\u0131bb\u0131, “h\u00fccre d\u00fczeyinde \u00c7in t\u0131bb\u0131” veya k\u0131saca “mikro toz \u00c7in t\u0131bb\u0131” olarak adland\u0131r\u0131l\u0131r.<\/p>\n

\"\"<\/p>\n

Baz\u0131 insanlar 1\u03bcm’den b\u00fcy\u00fck partik\u00fcl boyutuna sahip tozlar\u0131 “ince toz” ve 1\u03bcm’den k\u00fc\u00e7\u00fck partik\u00fcl boyutuna sahip ince tozlar\u0131 “ultrafin toz” olarak adland\u0131r\u0131r. Asl\u0131nda, geleneksel \u00c7in ila\u00e7lar\u0131n\u0131n par\u00e7ac\u0131k boyutu a\u00e7\u0131s\u0131ndan, \u015fu anda ara\u015ft\u0131rmalar\u0131n zirvesinde olan mikro ve nano geleneksel \u00c7in ila\u00e7lar\u0131, geleneksel \u00c7in ila\u00e7lar\u0131n\u0131n ultra-mikro m\u00fcstahzarlar\u0131 olarak da s\u0131n\u0131fland\u0131r\u0131lmaktad\u0131r. Lu Fuer et al. “Mikron \u00c7in t\u0131bb\u0131 m\u00fcstahzarlar\u0131n\u0131n”, modern y\u00fcksek teknoloji ve geleneksel i\u015fleme ve haz\u0131rlama teknikleri kullan\u0131larak geli\u015ftirilen yeni bir dozaj formu olan h\u00fccre dereceli mikro toz m\u00fcstahzarlar\u0131na ait oldu\u011funa inan\u0131yoruz. Genel olarak, partik\u00fcl boyutu 1-75\u03bcm olmal\u0131d\u0131r. Kapsam dahilindeki geleneksel \u00c7in ila\u00e7lar\u0131, geleneksel \u00c7in ila\u00e7lar\u0131n\u0131n do\u011fal farmakodinamik materyal temelini koruyabilir. “Mikron \u00c7in t\u0131bb\u0131”, \u00c7in t\u0131bbi malzemelerinin h\u00fccre duvar\u0131 k\u0131r\u0131lma oran\u0131n\u0131 %90’dan fazla art\u0131ran mikron \u00c7in t\u0131bbi malzemeleri, \u00c7in ila\u00e7lar\u0131n\u0131n mikron \u00f6zleri ve mikron \u00c7in t\u0131bb\u0131 m\u00fcstahzarlar\u0131n\u0131 i\u00e7erir. S\u00f6zde “nano \u00c7in t\u0131bb\u0131”, nanoteknolojinin uygulanmas\u0131yla \u00fcretilen 100 nm’den daha k\u00fc\u00e7\u00fck par\u00e7ac\u0131k boyutuna sahip geleneksel \u00c7in ila\u00e7lar\u0131n\u0131n etkili bile\u015fenleri, etkili par\u00e7alar\u0131, orijinal ila\u00e7lar\u0131 ve bile\u015fik preparasyonlar\u0131n\u0131 ifade eder. Nanometrele\u015ftirmeden sonra bir t\u00fcr \u00c7in t\u0131bb\u0131 tozudur. Yukar\u0131daki bak\u0131\u015f a\u00e7\u0131s\u0131na g\u00f6re, baz\u0131 ara\u015ft\u0131rmac\u0131lar ultra ince tozu mikron d\u00fczeyine (>1\u03bcm), mikron alt\u0131 d\u00fczeyine (0.1-1\u03bcm) ve nano d\u00fczeyine (1-100nm) ay\u0131r\u0131r ve ultra ince toz teknolojisini mikron teknolojisine ay\u0131r\u0131r. , Mikron alt\u0131 teknolojisi ve nanoteknoloji.<\/p>\n

Mevcut ara\u015ft\u0131rma ilerlemesinden yola \u00e7\u0131karak, \u00c7in t\u0131bb\u0131 ultra ince \u00f6\u011f\u00fct\u00fcc\u00fclerin bir\u00e7ok ad\u0131 olmas\u0131na ra\u011fmen, ilgili kavramlar ve \u00e7a\u011fr\u0131\u015f\u0131mlar ayn\u0131 de\u011fildir, \u00e7o\u011fu \u00c7in t\u0131bb\u0131n\u0131n ultra ince \u00f6\u011f\u00fctme i\u015fleminin \u00c7in t\u0131bb\u0131n\u0131n h\u00fccre d\u00fczeyinde toz haline getirilmesine at\u0131fta bulundu\u011funu d\u00fc\u015f\u00fcnmektedir. Partik\u00fcl boyutu 75\u03bcm’nin alt\u0131ndad\u0131r. Ara\u015ft\u0131rma \u00e7al\u0131\u015fmalar\u0131n\u0131n s\u00fcrekli derinle\u015ftirilmesiyle, geleneksel \u00c7in t\u0131bb\u0131n\u0131n ultra ince \u00f6\u011f\u00fctme kavram\u0131 veya tan\u0131m\u0131 daha bilimsel ve do\u011fru olacakt\u0131r.<\/p>\n

\u00c7in t\u0131bb\u0131 ultra ince \u00f6\u011f\u00fct\u00fcc\u00fc, ila\u00e7lar\u0131n sal\u0131nmas\u0131na ve emilmesine elveri\u015fli olan y\u00fcksek h\u00fccre duvar\u0131 k\u0131r\u0131lma oran\u0131na sahiptir. S\u0131radan ezilmi\u015f t\u0131bbi toz, d\u00fc\u015f\u00fck bir h\u00fccre duvar\u0131 k\u0131r\u0131lma oran\u0131na sahiptir. \u0130la\u00e7 v\u00fccuda girdi\u011finde, t\u0131bbi tozun toz par\u00e7ac\u0131klar\u0131 suyu emer ve geni\u015fler ve aktif maddeler dif\u00fczyon yoluyla s\u00fcrekli olarak h\u00fccre duvar\u0131ndan ve h\u00fccre zar\u0131ndan sal\u0131n\u0131r. Dif\u00fczyon, h\u00fccre i\u00e7i ve d\u0131\u015f\u0131 aras\u0131nda bir konsantrasyon fark\u0131 gerektirir. H\u00fccrenin i\u00e7i ve d\u0131\u015f\u0131 aras\u0131ndaki konsantrasyon fark\u0131 k\u00fc\u00e7\u00fck veya dengeli oldu\u011funda, aktif bile\u015fenin sal\u0131n\u0131m h\u0131z\u0131 \u00e7ok yava\u015f olacak, hatta duracakt\u0131r. \u0130\u00e7 h\u00fccrede bulunan aktif bile\u015fen, bazen serbest b\u0131rak\u0131lmadan \u00f6nce at\u0131l\u0131r, bu nedenle \u00e7o\u011fu zaman ula\u015f\u0131lamaz. Etkili bir terap\u00f6tik konsantrasyona.<\/p>\n

\"\"<\/p>\n

\u00c7in t\u0131bb\u0131 ultra ince \u00f6\u011f\u00fct\u00fcc\u00fcden sonra h\u00fccre duvar\u0131 k\u0131r\u0131lma oran\u0131 y\u00fcksektir ve aktif maddeler v\u00fccuda girmeden \u00f6nce a\u00e7\u0131\u011fa \u00e7\u0131kar. V\u00fccuda girdikten sonra, \u00e7\u00f6z\u00fcn\u00fcr bile\u015fenler h\u0131zla \u00e7\u00f6z\u00fcl\u00fcr. B\u00fcy\u00fck yap\u0131\u015fma ve gastrointestinal sistemin i\u00e7 duvar\u0131n\u0131n mukozas\u0131na s\u0131k\u0131ca yap\u0131\u015f\u0131r, b\u00f6ylece gastrointestinal kanalda kalma s\u00fcresi uzar, emilim daha yeterlidir ve emilim miktar\u0131 artar. Ezme s\u0131ras\u0131nda h\u00fccre duvar\u0131n\u0131n \u00e7o\u011fu tahrip oldu\u011fundan, etkili bile\u015fenlerin h\u00fccre duvar\u0131 ve h\u00fccre zar\u0131 serbest b\u0131rakma i\u015fleminden ge\u00e7mesine gerek yoktur. Bu \u015fekilde, ultra ince pulverizasyon, ila\u00e7 sal\u0131m h\u0131z\u0131 ve sal\u0131m miktar\u0131 a\u00e7\u0131s\u0131ndan s\u0131radan pulverizasyondan \u00e7ok daha \u00fcst\u00fcnd\u00fcr. Mineral<\/a> ila\u00e7, ilac\u0131n emilmesine ve iyile\u015ftirici etkinin iyile\u015ftirilmesine elveri\u015fli olan ultra ince \u00f6\u011f\u00fctmeden sonra bile mikrometrelere ula\u015fabilir.<\/p>\n","protected":false},"excerpt":{"rendered":"

Geleneksel \u00c7in t\u0131bb\u0131n\u0131n ultra ince \u00f6\u011f\u00fct\u00fclmesi ile ilgili olarak, ara\u015ft\u0131rmac\u0131lar, ultra ince \u00c7in t\u0131bb\u0131 par\u00e7ac\u0131klar\u0131, tek aromal\u0131 \u00c7in t\u0131bb\u0131 ultra ince par\u00e7alar\u0131 ve ultra ince \u00c7in t\u0131bb\u0131 tozlar\u0131 gibi farkl\u0131 ara\u015ft\u0131rma perspektiflerinden farkl\u0131 isimler ve kavramlar vermi\u015flerdir.<\/p>\n","protected":false},"author":6,"featured_media":111189,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[830],"tags":[1062,1064,1063],"class_list":["post-113728","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news","tag-cin-tibbi","tag-cin-tibbi-ultra-ince-ogutucu","tag-ultra-ince-ogutme-tr"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/posts\/113728","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/comments?post=113728"}],"version-history":[{"count":0,"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/posts\/113728\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/media\/111189"}],"wp:attachment":[{"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/media?parent=113728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/categories?post=113728"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.alpapowder.com\/tr\/wp-json\/wp\/v2\/tags?post=113728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}